Cookstown get their Premier League title defence underway as they host Belfast Harlequins.
The Mid-Ulster side won the division with a near-perfect record last season and lost just once in their 18 games.
They face a Belfast Harlequins side who got their campaign up and running with a 3-2 win against Bangor last weekend.
Three goals from Matty Gray, James Hutchinson and Aaron Murphy sealed the victory in new Coach Paddy Jack’s first league game in charge.
Elsewhere in the division Instonians travel to Kilkeel as they look to make it two wins from two since their recent relegation.
The Belfast Club got off to a flying start midweek when they beat P.S.N.I 6-1 with goals from Stephen Kelso (3), Josh Kidd (2) and David Arneill.
Today they face a Kilkeel side that came second in the division last campaign and are likely to cause a lot of problems for their visitors.
Forward Luke Russell was amongst the top goal scorers in the division last year as he netted 18 times on route to their EYHL2 qualification.
The third game of the day sees Portadown host Queen’s University at Edenvilla.
The tie marks the start to the Men’s Premier League season for both sides following their Anderson Cup fixtures in recent weeks.
During that time the two sides faced off with the students coming out on top 3-0 just two weeks ago.
That day two goals from Harry Scott and a strike from Matthew Vincent was enough to seal the University sides place in the semi-finals of the competition.
On Friday night South Antrim beat Bangor 3-2 at Friends’ School Lisburn thanks to a late strike from Rory Brown following good work from Andrew Clarke.
